Sino Biopharmaceutical Limited has announced the successful enrollment of the first patient in the Phase I clinical trial of TRD208, a first-in-class, non-opioid, multi-target, multi-modal analgesic. TRD208, independently developed by the company, is designed to block multiple pain-related transmission pathways in the central nervous system, including NaV1.7 and NaV1.8, and demonstrates peripheral analgesic effects. The trial is being conducted in China, and the company expects TRD208 to address unmet clinical needs in acute pain management. No study results have been presented at this stage.
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