Vaxcyte Begins Phase 3 Trial of VAX-31 Pneumococcal Vaccine in Adults

Reuters12-08

Vaxcyte Begins Phase 3 Trial of VAX-31 Pneumococcal Vaccine in Adults

Vaxcyte Inc. has announced the initiation of the OPUS Phase 3 pivotal, noninferiority clinical trial evaluating VAX-31 for the prevention of invasive pneumococcal disease (IPD) and pneumonia in adults. The trial, which aims to enroll approximately 4,000 participants, was designed in consultation with the U.S. Food and Drug Administration and will compare VAX-31 to current standard-of-care vaccines Capvaxive (PCV21) and Prevnar 20 (PCV20). Topline safety, tolerability, and immunogenicity results from the OPUS trial are expected in the fourth quarter of 2026. Additional Phase 3 studies are planned to begin in 2026, with results anticipated in 2027. No results from these studies have been presented yet.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Vaxcyte Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9598257-en) on December 08, 2025, and is solely responsible for the information contained therein.

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