Evaxion A/S has announced new preclinical data for its acute myeloid leukemia (AML) vaccine candidate, EVX-04. The results were presented in an oral session at the American Society of Hematology $(ASH)$ Annual Meeting and Exposition in Orlando, Florida. The data show that EVX-04, designed with Evaxion's proprietary AI-Immunology™ platform, induces strong specific T-cell responses and prevents tumor growth in preclinical models. EVX-04 targets multiple non-conventional endogenous retrovirus (ERV) tumor antigens and is developed as an off-the-shelf therapeutic cancer vaccine. According to the company, the off-the-shelf vaccine concept behind EVX-04 may also have potential applications in other hard-to-treat cancers.
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