Junshi Biosciences Reports Toripalimab Achieves Record Survival in NPC and ESCC Trials

Reuters12-06 11:11
Junshi Biosciences Reports Toripalimab Achieves Record Survival in NPC and ESCC Trials

Shanghai Junshi Biosciences Co., Ltd. announced new long-term survival results from the JUPITER-02 and JUPITER-06 clinical trials, evaluating toripalimab in combination with chemotherapy as first-line treatment for recurrent or metastatic nasopharyngeal carcinoma (NPC) and advanced or metastatic esophageal squamous cell carcinoma (ESCC), respectively. The updated data, including the 5-year overall survival follow-up from JUPITER-02, were presented at the European Society for Medical Oncology (ESMO) Asia Congress 2025. The JUPITER-02 trial enrolled 289 chemotherapy-naïve patients with recurrent or metastatic NPC, randomizing them to receive either toripalimab or placebo with gemcitabine and cisplatin, followed by monotherapy until disease progression or other discontinuation criteria. The primary endpoint was progression-free survival, with overall survival as a key secondary endpoint.

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