Actinium Pharmaceuticals Inc. announced the presentation of new preclinical data for ATNM-400, its Actinium-225 based antibody radioconjugate, at the 2025 San Antonio Breast Cancer Symposium (SABCS). The data demonstrated robust anti-tumor activity and a favorable tolerability profile across various preclinical breast cancer models, including hormone receptor-positive, triple-negative, and tamoxifen- and trastuzumab-resistant tumors. ATNM-400 targets a validated cancer antigen overexpressed in breast cancer and other solid tumors such as prostate cancer and non-small cell lung cancer. The company indicated plans to advance the development of ATNM-400 toward clinical readiness. The results were presented at the 2025 SABCS.
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