VolitionRx Ltd. has announced the preprint availability of a new manuscript detailing a novel method, Capture-Seq™, and new biomarkers for cancer detection. The study involved a training cohort of 70 individuals, including 49 patients with breast, prostate, lung, or colorectal cancer. Results showed that the analysis of ultrashort transcription factor-bound DNA in plasma detected all cancer patients (100% sensitivity) and produced no false positives (100% specificity), including those with early-stage disease. These initial findings have not yet been validated in larger independent studies. The company also reported achieving a 180-fold enrichment of target DNA fragments and indicated that the technology may expand its Nu.Q® portfolio. The results have been made available in a preprint and have not yet been presented in a peer-reviewed forum.
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