Ascletis Pharma Reports Positive Phase I Results for Oral IL-17 Inhibitor ASC50

Reuters12-15

Ascletis Pharma Reports Positive Phase I Results for Oral IL-17 Inhibitor ASC50

Ascletis Pharma Inc. has announced positive topline results from a randomized, double-blind, placebo-controlled Phase I clinical trial in the United States evaluating ASC50, a potential best-in-class oral small molecule IL-17 inhibitor. The study assessed the safety, tolerability, pharmacokinetics, and IL-17A target engagement profile of ASC50 in healthy participants who received single ascending doses ranging from 10 mg to 600 mg or placebo. The company stated that the elimination half-life of ASC50 ranged from 43 to 104 hours depending on the dose. Results from this study were announced on December 15, 2025. Ascletis will host a conference call to discuss the findings. The company noted that there is no guarantee of successful development, manufacturing, or commercialization of ASC50.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ascletis Pharma Inc. published the original content used to generate this news brief via IIS, the Issuer Information Service operated by the Hong Kong Stock Exchange (HKex) (Ref. ID: HKEX-EPS-20251215-11955373), on December 15, 2025, and is solely responsible for the information contained therein.

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ID: HKEX-EPS-20251215-11955373), on December 15, 2025, and is solely responsible for the information contained therein.</span></em>\n</div></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK1574","symbol_name":"生物医药B类股","start_time":0,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251215:nNDLb46kyg:1","article_id":"2591611872","we_media_id":"1032215980","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2591611872","pubTimestamp":1765788393,"columns":[],"sourceInfo":null,"weMediaInfo":{"media_name":"Reuters","introduction":"Reuters.com brings you the latest news from around the world, covering breaking news in markets, business, politics, entertainment and technology","home_visible":1,"id":"1032215980","head_image":"https://community-static.tradeup.com/news/4567337cbdf294b657b1fa87c5488b48"},"summary":"Ascletis Pharma Inc. has announced positive topline results from a randomized, double-blind, placebo-controlled Phase I clinical trial in the United States evaluating ASC50, a potential best-in-class oral small molecule IL-17 inhibitor. 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The company stated that the elimination half-life of ASC50 ranged from 43 to 104 hours depending on the dose. Results from this study were announced on December 15, 2025. Ascletis will host a conference call to discuss the findings. The company noted that there is no guarantee of successful development, manufacturing, or commercialization of ASC50.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ascletis Pharma Inc. published the original content used to generate this news brief via IIS, the Issuer Information Service operated by the Hong Kong Stock Exchange (HKex) (Ref. 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