Hologic AI Mammography Flags One-Third of Missed Breast Cancer Cases in Study

Reuters2025-12-16
Hologic AI Mammography Flags One-Third of Missed Breast Cancer Cases in Study

Hologic Inc. has announced new data from a clinical study evaluating its Genius AI Detection solution, an AI-powered mammography technology. The retrospective analysis, conducted at Massachusetts General Hospital and published in the American Journal of Roentgenology, reviewed 7,500 digital breast tomosynthesis screening exams performed between 2016 and 2019. The study found that among 100 false-negative cases-mammograms initially interpreted as negative but followed by a breast cancer diagnosis within a year-the Genius AI Detection solution flagged approximately one-third (32%) as containing suspicious areas, correctly identifying the location where cancer was later diagnosed. The study's results have already been presented. Study limitations include its single-center design, predominantly Caucasian patient population, and lack of evaluation of patient outcomes or integration into clinical workflows.

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