Amplia Therapeutics (ASX:ATX) entered into the second phase of a research collaboration with South Korean preclinical drug screening company Next & Bio, according to a Friday Australian bourse filing.
The firms are collaborating on investigating the ability of Amplia's FAK inhibitors to suppress the growth of patient-derived pancreatic cancer cells that possess genetic mutations in the kRAS gene, which are known to be present in over 90% of pancreatic cancers.
Amplia's FAK inhibitor narmafotinib showed promising activity in initial tests, per the filing. Further studies investigating the activity of a combination of narmafotinib with known inhibitors of the mutant kRAS gene will be conducted.
Its shares rose 2% in recent trading on Friday.
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