Spero Therapeutics Inc. announced that its development partner, GlaxoSmithKline Intellectual Property (No. 3) Limited $(GSK)$, has filed a New Drug Application (NDA) resubmission to the U.S. Food and Drug Administration for tebipenem HBr, an investigational oral carbapenem antibiotic for the treatment of complicated urinary tract infections, including pyelonephritis. The NDA resubmission triggers a $25 million milestone payment to Spero Therapeutics under its License Agreement with GSK, which is expected to be received in the first quarter of 2026.
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