** Drugmaker Insmed's INSM.O shares plunge 20.1% to $158.50 premarket after scrapping sinus drug development after mid-stage study failure
** Jefferies cuts PT to $241 from $269, a 21.4% upside to stock's last close of $198.46
** TD Cowen cuts PT to $219 from $230, a 10.3% upside to stock's last close
** INSM says its drug brenscocatib did not meet the study's primary or secondary endpoints in treating patients with a long-term sinus condition
** Brenscocatib was designed to reduce inflammation in the lungs and airways
** TD Cowen, however, says the program represented only a small component of INSM’s overall value and continues to see significant upside potential
** 18 of 19 brokerages rate the stock "buy" or higher, 1 "hold"; median PT is $228.5 - LSEG data
** As of last close, INSM down 1.1% YTD
(Reporting by Utkarsh Tushar Hathi)
((utkarshtushar.hathi@thomsonreuters.com))
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