Avadel Pharmaceuticals Completes Enrollment in Phase 3 Trial of LUMRYZ for Idiopathic Hypersomnia

Reuters2025-12-18

Avadel Pharmaceuticals Completes Enrollment in Phase 3 Trial of LUMRYZ for Idiopathic Hypersomnia

Avadel Pharmaceuticals plc announced the completion of patient enrollment in the Phase 3 REVITALYZ trial, which is evaluating LUMRYZ (sodium oxybate) extended-release oral suspension as a potential treatment for idiopathic hypersomnia. The study is a double-blind, placebo-controlled, randomized withdrawal, multicenter trial assessing both patients switching from immediate-release oxybates and those not currently taking oxybates. The primary endpoint is the change in total score on the Epworth Sleepiness Scale at Week 14, with secondary endpoints evaluating additional efficacy measures. Data from the trial are expected in the second quarter of 2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Avadel Pharmaceuticals plc published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 9604287) on December 18, 2025, and is solely responsible for the information contained therein.

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