Insmed Discontinues Brensocatib CRSsNP Program After Phase 2b Trial Misses Endpoints

Reuters12-18 05:01

<a href="https://laohu8.com/S/INSM">Insmed</a> Discontinues Brensocatib CRSsNP Program After Phase 2b Trial Misses Endpoints

Insmed Inc. announced that its Phase 2b BiRCh study of brensocatib in patients with chronic rhinosinusitis without nasal polyps (CRSsNP) did not meet its primary or secondary efficacy endpoints in either the 10 mg or 40 mg treatment arms. The company reported that brensocatib was well tolerated, with no new safety signals observed. As a result, Insmed has discontinued its development program of brensocatib in CRSsNP. The company intends to present the study data at a future congress. Additionally, Insmed announced the acquisition of INS1148, a Phase 2 ready monoclonal antibody targeting respiratory and immunological and inflammatory diseases. The company plans to advance INS1148 into Phase 2 development programs for interstitial lung disease and moderate-to-severe asthma.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Insmed Inc. published the original content used to generate this news brief via PR Newswire (Ref. ID: NY50122) on December 17, 2025, and is solely responsible for the information contained therein.

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