Alphamab Oncology IND Application for JSKN027 Accepted by Chinese Regulator

Reuters12-17

Alphamab Oncology IND Application for JSKN027 Accepted by Chinese Regulator

Alphamab Oncology announced that its Investigational New Drug $(IND)$ application for JSKN027, an independently developed PD-L1/VEGFR2 bispecific antibody-drug conjugate, has been officially accepted by the Center for Drug Evaluation $(CDE)$ of the National Medical Products Administration of China. The company plans to initiate a phase I clinical study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of JSKN027 in patients with advanced malignant solid tumors.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Alphamab Oncology published the original content used to generate this news brief via IIS, the Issuer Information Service operated by the Hong Kong Stock Exchange (HKex) (Ref. ID: HKEX-EPS-20251217-11958718), on December 17, 2025, and is solely responsible for the information contained therein.

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The company plans to initiate a phase I clinical study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity of JSKN027 in patients with advanced malignant solid tumors.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Alphamab Oncology published the original content used to generate this news brief via IIS, the Issuer Information Service operated by the Hong Kong Stock Exchange (HKex) (Ref. 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