Entera Bio Unveils Oral PTH Tablet Achieving Sustained Calcium Elevation in Preclinical Study

Reuters12-22 21:30

Entera Bio Unveils Oral PTH Tablet Achieving Sustained Calcium Elevation in Preclinical Study

Entera Bio Ltd. has announced new preclinical data supporting the development of its proprietary first-in-class oral, long-acting parathyroid hormone $(PTH)$ tablet for patients with hypoparathyroidism, part of the EB612 program. The company reported that its novel PTH analog, delivered using the N-Tab® platform, achieved a sustained increase in serum calcium levels for over three days from a single oral dose in animal studies. This effect was not observed with unmodified PTH(1-34) controls. The findings suggest the potential for a once-daily oral PTH tablet as an alternative to daily injections. Entera Bio stated that these results will be presented at an upcoming medical conference.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Entera Bio Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW1001156107-en) on December 22, 2025, and is solely responsible for the information contained therein.

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The company reported that its novel PTH analog, delivered using the N-Tab® platform, achieved a sustained increase in serum calcium levels for over three days from a single oral dose in animal studies. This effect was not observed with unmodified PTH(1-34) controls. The findings suggest the potential for a once-daily oral PTH tablet as an alternative to daily injections. Entera Bio stated that these results will be presented at an upcoming medical conference.\n      \n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Entera Bio Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. 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