CARsgen Submits Dual IND Applications for Allogeneic BCMA CAR-T Therapy CT0596

Reuters2025-12-29

CARsgen Submits Dual IND Applications for Allogeneic BCMA CAR-T Therapy CT0596

CARsgen Therapeutics Holdings Ltd. has submitted two separate Investigational New Drug $(IND)$ applications to the National Medical Products Administration (NMPA) for its allogeneic BCMA-targeted CAR-T cell therapy product, CT0596. The applications seek to initiate Phase Ib/II clinical trials for the treatment of relapsed/refractory multiple myeloma (R/R MM) and primary plasma cell leukemia (pPCL). This regulatory submission marks the start of the registration clinical development phase for CT0596, which has shown promising safety and efficacy signals in preliminary investigator-initiated trials.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. CARsgen Therapeutics Holdings Ltd. published the original content used to generate this news brief via PR Newswire (Ref. ID: CN53679) on December 29, 2025, and is solely responsible for the information contained therein.

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