** Drugmaker Ionis Pharmaceuticals' IONS.O shares rise 4.8% to $85.41, hitting a nearly seven-year high
** Co's partner GSK GSK.L announces positive results for hepatitis B therapy in late-stage trial
** The drug, licensed from IONS, blocks replication of the hepatitis B virus and reduces production of proteins linked to the infection
** The drug could generate over 2 billion pounds ($2.70 billion) in annual sales, says GSK
** GSK plans to file for regulatory approval in first quarter of 2026
** IONS stock price more than doubled in 2025
(Reporting by Utkarsh Tushar Hathi)
((utkarshtushar.hathi@thomsonreuters.com))
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