Ionis and GSK Report Positive Phase 3 Results for Bepirovirsen in Chronic Hepatitis B

Reuters01-07

Ionis and GSK Report Positive Phase 3 Results for Bepirovirsen in Chronic Hepatitis B

Ionis Pharmaceuticals Inc. announced that its partner, GSK, has reported positive topline results from the B-Well 1 and B-Well 2 Phase 3 clinical studies evaluating bepirovirsen, an investigational antisense oligonucleotide for the treatment of chronic hepatitis B $(CHB)$. The primary endpoint was met in both trials, with bepirovirsen demonstrating a statistically significant and clinically meaningful functional cure rate. The studies included over 1,800 patients from 29 countries. Global regulatory filings for bepirovirsen are planned to begin in the first quarter of 2026. The results from these studies have already been announced.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ionis Pharmaceuticals Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 20260106121974) on January 07, 2026, and is solely responsible for the information contained therein.

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