FDA Clears IND for Ascentage Pharma’s BTK Degrader APG-3288

Reuters01-07

FDA Clears IND for <a href="https://laohu8.com/S/AAPG">Ascentage Pharma</a>’s BTK Degrader APG-3288

Ascentage Pharma Group International has received Investigational New Drug $(IND)$ clearance from the U.S. Food and Drug Administration (FDA) for its novel next-generation Bruton tyrosine kinase (BTK)-targeted protein degrader, APG-3288. This regulatory approval enables the company to initiate a global, multicenter Phase I clinical study evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of APG-3288 in patients with relapsed or refractory B-cell malignancies. The clearance marks a significant milestone in Ascentage Pharma’s efforts to expand its pipeline of innovative therapies for hematologic malignancies.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ascentage Pharma Group International published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 9621162) on January 07, 2026, and is solely responsible for the information contained therein.

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Ascentage Pharma Group International published the original content use","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"IE00BKPKM429.USD":"NEUBERGER BERMAN GLOBAL SUSTAINABLE EQUITY \"A\" (USD) ACC","NDAQ":"纳斯达克OMX交易所","IE00B64PRP62.GBP":"GUINNESS GLOBAL MONEY MANAGERS \"C\" (GBP) ACC","BK4588":"碎股","LU2095319765.USD":"Natixis Thematics Subscription Economy R/A USD","SG9999014039.USD":"UNITED GLOBAL DURABLE EQUITIES (USDHDG) INC","SG9999014005.SGD":"United Global Durable Equities Fund Acc SGD","IE00B3QW5Z07.USD":"GUINNESS GLOBAL MONEY MANAGERS \"C\" (USD) ACC","BK4112":"金融交易所和数据","SG9999014021.USD":"UNITED GLOBAL DURABLE EQUITIES (USDHDG) ACC","LU2210150020.SGD":"Natixis Thematics Subscription Economy R/A SGD","IE00BGHQF748.EUR":"GUINNESS GLOBAL MONEY MANAGERS \"C\" (EUR) ACC","SG9999014013.SGD":"United Global Durable Equities Fund Dis SGD","LU2210149790.SGD":"Natixis Thematics Subscription Economy R/A SGD-H","BK1161":"生物科技","06855":"亚盛医药-B","LU0314104364.USD":"MANULIFE GF AMERICAN GROWTH \"AA\" (USD) INC","BK4585":"ETF&股票定投概念","BK1574":"生物医药B类股"},"translate_title":"FDA批准亚盛医药BTK降解剂APG-3288的IND","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"06855":0.9,"NDAQ":0.9},"content_text":"FDA Clears IND for Ascentage Pharma’s BTK Degrader APG-3288\n    \n\nAscentage Pharma Group International has received Investigational New Drug $(IND)$ clearance from the U.S. Food and Drug Administration (FDA) for its novel next-generation Bruton tyrosine kinase (BTK)-targeted protein degrader, APG-3288. This regulatory approval enables the company to initiate a global, multicenter Phase I clinical study evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of APG-3288 in patients with relapsed or refractory B-cell malignancies. The clearance marks a significant milestone in Ascentage Pharma’s efforts to expand its pipeline of innovative therapies for hematologic malignancies.\n      \n\n\nDisclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Ascentage Pharma Group International published the original content used to generate this news brief via GlobeNewswire (Ref. 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