TransThera Sciences (Nanjing) Inc. has announced the completion of a poster presentation at the 2026 American Society of Clinical Oncology Gastrointestinal Cancers Symposium (ASCO GI), detailing clinical data analysis from a Phase II study of tinengotinib monotherapy in patients with advanced cholangiocarcinoma. The presentation focused on circulating tumour DNA (ctDNA) biomarker analyses and tinengotinib’s efficacy in treating patients with FGFR2 fusions exhibiting primary or acquired resistance to prior FGFR inhibitors, as well as those with other FGFR alterations or wild-type FGFR. Genomic alterations in ctDNA and efficacy correlations by mutational status were discussed. The results support further investigation in an ongoing Phase III clinical trial.
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