Summit Therapeutics and GSK Partner to Evaluate Ivonescimab and B7-H3 ADC in Solid Tumors

Reuters01-12
<a href="https://laohu8.com/S/SMMT">Summit</a> <a href="https://laohu8.com/S/LENZ">Therapeutics</a> and GSK Partner to Evaluate Ivonescimab and B7-H3 ADC in Solid Tumors

Summit Therapeutics Inc. has announced a clinical trial collaboration with GSK to evaluate the combination of ivonescimab, Summit’s investigational PD-1/VEGF bispecific antibody, with GSK’s novel B7-H3-targeted antibody-drug conjugate, risvutatug rezetecan (GSK'227), across multiple solid tumor types, including small cell lung cancer. Under the agreement, Summit will provide ivonescimab for the study, while GSK will oversee clinical operations. Both companies will retain rights to their respective products, and the agreement is mutually non-exclusive. Patient dosing in the study is expected to begin in mid-2026.

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