Vor Biopharma Unveils Telitacicept Data Targeting B Cell-Driven Autoimmune Diseases

Reuters01-16
Vor Biopharma Unveils Telitacicept Data Targeting B Cell-Driven Autoimmune Diseases

Vor Biopharma Inc. presented updates on its lead autoimmune programs targeting B cell-driven diseases through BAFF/APRIL inhibition with telitacicept, a selective BAFF/APRIL inhibitor. The company highlighted ongoing and upcoming global Phase 3 clinical trials in myasthenia gravis, with topline data expected in the first half of 2027, and in Sjögren's disease, which is set to begin in the first half of 2026. Telitacicept has shown clinical validation across more than eight autoimmune indications in China and has been administered to tens of thousands of patients with a manageable safety and tolerability profile. Adverse events reported in clinical trials were primarily mild to moderate, including upper respiratory tract infection, injection site reaction, urinary tract infection, cough, and diarrhea. The company reported a strong cash position of $450 million as of December 2025, expected to fund operations into mid-2028. You can access the full presentation through the link below.

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