FACTBOX-Major deals involving U.S. drugmakers and biotechs over the past decade

Reuters01-15
FACTBOX-Major deals involving U.S. drugmakers and biotechs over the past decade

Changes dateline, adds details on Boston Scientific deal in paragraph 1

Jan 15 (Reuters) - Boston Scientific BSX.N is buying medical equipment maker Penumbra PEN.N in a deal valued at about $14.5 billion, to expand its vascular pipeline.

The move adds to a growing list of high-profile transactions over the past decade by U.S. pharmaceutical companies to acquire promising therapies in fields ranging from oncology, neurology to rare diseases and obesity.

Below are some of the major deals involving U.S.-based pharma and biotech firms from the past decade

Year

Acquirer

Target

Deal Value

Description

2026

Boston ScientificBSX.N

Penumbra PEN.N

$14.5 billion

To expand vascular pipeline

2025

Abbott < ABT.N>

Exact Sciences EXAS.O

up to $23 billion

To gain access to Exact Sciences' cancer tests, including flagship colorectal cancer test Cologuard

2025

Merck MRK.N

Cidara Therapeutics CDTX.O

$9.2 billion

To gain access to Cidara's experimental drug for flu prevention

2025

Pfizer PFE.N

Metsera MTSR.O

$10 billion

To gain a foothold in the fast-growing obesity treatment market

2025

Merck & Co MRK.N

Verona Pharma I9SAy.F

About $10 billion

Strengthens Merck's respiratory portfolio amid looming Keytruda patent cliff

2025

Johnson & Johnson JNJ.N

Intra-Cellular Therapies

$14.6 billion

Expands J&J's footprint in brain disease treatments

2024

Novo Holdings

Catalent

$16.5 billion (including debt), $11.5 billion (excluding debt)

Boosts manufacturing capacity for Novo Nordisk's popular obesity drug Wegovy

2023

Merck & Co

Prometheus Biosciences

$10.8 billion

Adds experimental treatment for ulcerative colitis and Crohn's disease and builds up presence in immunology

2023

Bristol Myers Squibb BMY.N

Karuna Therapeutics

$14 billion

BMY gains a promising antipsychotic medicine as patents on its older therapies near their expiry

2023

Pfizer PFE.N

Seagen

$43 billion

Builds Pfizer's cancer portfolio amid decline in sales for COVID-related products and generic competition

2022

Amgen AMGN.O

Horizon Therapeutics

$27.8 billion

Buyout, biggest in the sector in 2022, fortifies rare diseases portfolio

2022

Pfizer

Biohaven Pharmaceutical Holding

$11.6 billion

Pfizer bets big on a new class of migraine drugs

2021

Merck & Co

Acceleron Pharma

About $11.5 billion

Diversifies Merck's portfolio beyond cancer

2021

Ginkgo Bioworks DNA.N

Soaring Eagle Acquisition

$17.5 million

Ginkgo goes public through a merger with a blank-check vehicle backed by former Hollywood executives Harry Sloan and Jeff Sagansky

2020

AstraZeneca AZN.L

Alexion Pharmaceuticals

$39 billion

AstraZeneca's largest ever deal to diversify away from its cancer business, betting on rare-disease and immunology drugs

2020

Bristol Myers Squibb

MyoKardia

About $13 billion

Bolster Bristol's portfolio of heart disease treatments

2020

Gilead GILD.O

Immunomedics

$21 billion

Strengthens Gilead's cancer portfolio

2019

Mylan

Pfizer's Upjohn business

About $12 billion

Mylan's acquisition of Pfizer's Upjohn business was structured as a stock-based merger, resulting in the formation of Viatris VTRS.O. Upjohn was essentially spun off to Pfizer shareholders and then merged with Mylan

2019

AbbVie ABBV.N

Allergan

$63 billion, $83 billion (including debt)

AbbVie gains control of Botox and diversifies its portfolio beyond its then-blockbuster drug, Humira

2019

Pfizer

Array Biopharma

$11.4 billion

Pfizer gains oncology asset

2019

Bristol Myers Squibb

Celgene Corp

$74 billion

One of the largest pharmaceutical mergers in history

2017

Johnson & Johnson's JNJ.N

Actelion

$30 billion

Johnson & Johnson's subsidiary, Janssen Holding, acquires Actelion; Actelion's R&D unit spun off into Idorsia

2017

Gilead Sciences

Kite Pharma

$11.9 billion

Strengthens Gilead's position in the field of cell therapy, particularly in CAR-T treatments for cancer

2016

Pfizer

Medivation

$14 billion

Pfizer acquires blockbuster prostate cancer drug Xtandi

2015

Shire

Baxalta

$32 billion

Catapults Shire to leading position in treating rare diseases

2015

AbbVie

Pharmacyclics

$21 billion

AbbVie gets access to what is expected to be one of the world's top-selling cancer drugs and expanding its reach in the profitable oncology field

2015

Valeant Pharmaceuticals (now Bausch Health)

Salix Pharmaceuticals

$14.5 billion

Makes Valeant a leader in gastro-intestinal drugs

2015

Pfizer

Hospira

$15 billion

Deal creates leading global established pharmaceutical business for Pfizer

(Reporting by Puyaan Singh, Siddhi Mahatole and Mariam Sunny in Bengaluru; Editing by Shailesh Kuber and Devika Syamnath)

((Puyaan.Singh@thomsonreuters.com;))

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