Teva Pharmaceutical (TEVA) on late Wednesday said that its drug, Ajovy, significantly reduced monthly migraine and headache days in children and adolescents with episodic migraine phase 3 study, with results published in the New England Journal of Medicine.
According to the company, Ajovy cut monthly migraine days by 2.5 days versus 1.4 days for placebo over 12 weeks, and reduced moderate-to-severe headache days by 2.6 days versus 1.5 days.
Nearly 47% of patients achieved at least a 50% reduction in migraine days, compared with 27% on placebo, the company said.
The data supported the FDA's August 2025 approval of Ajovy for preventive treatment of episodic migraine in children aged 6-17 weighing at least 99 pounds.
Teva said no new safety issues were observed, and the drug's safety profile is consistent with adult studies.
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