Atai Beckley Reports Positive Phase 2b Results for BPL-003 Nasal Spray in Treatment-Resistant Depression

Reuters01-16

Atai Beckley Reports Positive Phase 2b Results for BPL-003 Nasal Spray in Treatment-Resistant Depression

AtaiBeckley Inc. announced the presentation of new clinical and preclinical data at the 64th Annual Meeting of the American College of Neuropsychopharmacology (ACNP), held January 12-15, 2026. The company presented results from a Phase 2b study evaluating BPL-003 (mebufotenin benzoate) nasal spray in patients with treatment-resistant depression. Data showed that single doses of 8 mg or 12 mg produced significant, rapid, and sustained antidepressant effects compared to a sub-perceptual dose control, with both active doses being well-tolerated. These results were presented in both a poster session and the ACNP’s Hot Topics Session. Additionally, preclinical findings on the pharmacology and potential neuroplasticity effects of 5-MeO-DMT were also presented at the conference.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Atai Beckley NV published the original content used to generate this news brief via GlobeNewswire (Ref. ID: GNW9627051-en) on January 16, 2026, and is solely responsible for the information contained therein.

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