Gilead Sciences (GILD) said late Wednesday that The New England Journal of Medicine published full results from its phase 3 trial of Trodelvy and Keytruda for first-line PD-L1+ metastatic triple-negative breast cancer that met its primary endpoint of progression-free survival, with a 35% reduced risk of disease progression or death compared with Keytruda plus chemotherapy treatment.
Median PFS with Trodelvy plus Keytruda was 11.2 months compared with 7.8 months for Keytruda in combination with chemotherapy, the company said.
The safety profile of the drug regimen was consistent with the known safety profile of each agent, and no new safety signals were identified, according to a statement.
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