Cardiff Oncology Reports Positive Phase 2 Results for Onvansertib in First-Line RAS-Mutated mCRC

Reuters01-28

<a href="https://laohu8.com/S/CRDF">Cardiff Oncology</a> Reports Positive Phase 2 Results for Onvansertib in First-Line RAS-Mutated mCRC

Cardiff Oncology Inc. announced positive interim results from its randomized Phase 2 clinical trial (CRDF-004) evaluating onvansertib in combination with standard of care regimens (FOLFIRI/bevacizumab or FOLFOX/bevacizumab) in patients with first-line RAS-mutated metastatic colorectal cancer. The company reported dose-dependent improvements in overall response rates and trends in progression-free survival for patients receiving onvansertib with FOLFIRI/bevacizumab, compared to standard regimens. Onvansertib was well-tolerated, with no major or unexpected toxicities observed. Based on these findings, the 30 mg dose of onvansertib was selected for further development. Cardiff Oncology stated that final data and registrational plans are expected to be provided in the first half of 2026. The results were presented during a conference call and webcast on January 27, 2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Cardiff Oncology Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 9642898) on January 27, 2026, and is solely responsible for the information contained therein.

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