** Shares of drug developer Cardiff Oncology CRDF.O fall 32% to $2 premarket
** Cardiff's CEO and CFO both step down, effective immediately
** Co says board member Mani Mohindru appointed as interim CEO while it searches for replacements
** Separately, CRDF says a mid-stage trial showed that adding its experimental drug, onvansertib, to a standard first‑line chemotherapy regimen improved response rates and delayed disease progression in patients with a hard-to-treat form of colorectal cancer
** Says patients who received the higher 30-milligram dose of onvansertib alongside standard chemotherapy had a 72% response rate, compared with 43% for those on standard treatment alone
** Adds that it plans to launch a larger, late-stage trial later this year
** In 2025, CRDF fell 34%
(Reporting by Kamal Choudhury in Bengaluru)
((Kamal.Choudhury@thomsonreuters.com;))
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