Pfizer Reports BRAFTOVI Regimen Improves Progression-Free Survival in BRAF V600E-Mutant Metastatic Colorectal Cancer

Reuters02-17

Pfizer Reports BRAFTOVI Regimen Improves Progression-Free Survival in BRAF V600E-Mutant Metastatic Colorectal Cancer

Pfizer Inc. announced positive topline results from Cohort 3 of the pivotal Phase 3 BREAKWATER trial evaluating BRAFTOVI (encorafenib) in combination with cetuximab and FOLFIRI in patients with previously untreated BRAF V600E-mutant metastatic colorectal cancer. The BRAFTOVI regimen demonstrated a statistically significant and clinically meaningful improvement in progression-free survival compared to FOLFIRI with or without bevacizumab. Overall survival also showed clinically meaningful improvement. The results were recently shared by the company.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Pfizer Inc. published the original content used to generate this news brief via Business Wire (Ref. ID: 202602170645BIZWIRE_USPR_____20260217_BW508407) on February 17, 2026, and is solely responsible for the information contained therein.

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