Aclaris Initiates Phase 1b Asthma Trial of Bispecific Antibody ATI-052

Reuters02-24

Aclaris Initiates Phase 1b Asthma Trial of Bispecific Antibody ATI-052

Aclaris Therapeutics Inc. has initiated a randomized, double-blind, placebo-controlled Phase 1b proof-of-concept trial evaluating ATI-052, an investigational bispecific anti-TSLP/IL-4Rα antibody, in approximately 16 asthma patients on GINA steps 2–4 therapy prior to screening. The study will assess safety, tolerability, pharmacokinetics, pharmacodynamic biomarkers (including FeNO and blood eosinophil count), and efficacy measures such as FEV1. The company said top-line results from this asthma trial and an ongoing Phase 1b proof-of-concept trial in atopic dermatitis are expected in the second half of 2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Aclaris Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 202602240700PRIMZONEFULLFEED9659470) on February 24, 2026, and is solely responsible for the information contained therein.

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