AC Immune doses first participant in Phase 1 trial of NLRP3 inhibitor ACI-19764

Reuters02-24

AC Immune doses first participant in Phase 1 trial of NLRP3 inhibitor ACI-19764

AC Immune SA announced that the first participant has been dosed in a Phase 1 clinical trial of ACI-19764, an orally administered, brain-penetrant small-molecule inhibitor of the NLRP3 inflammasome. The Europe-based study in healthy volunteers will assess safety, tolerability, pharmacokinetics and pharmacodynamics, with single ascending doses in Part A and multiple ascending doses in Part B, and will include measures such as plasma and cerebrospinal fluid pharmacokinetics and IL-1β inhibition. Results have not yet been presented; initial Phase 1 data are expected in the second half of 2026.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. AC Immune Ltd. published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 202602240700OMX_____CNEWS_EN_GNW1001166350_en) on February 24, 2026, and is solely responsible for the information contained therein.

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