Ionis Pharma Q4 revenue beats expectations, helped by TRYNGOLZA EU launch

Reuters02-25
Ionis Pharma Q4 revenue beats expectations, helped by TRYNGOLZA EU launch

Overview

  • Biotech firm Ionis Q4 revenue beat analyst expectations

  • Adjusted operating income for Q4 beat analyst estimates

  • Company preparing for multiple product launches in 2026

Outlook

  • Ionis expects 2026 revenue between $800 mln and $825 mln

  • Company anticipates operating loss on a non-GAAP basis of $500 mln to $550 mln in 2026

  • Ionis plans modest increase in non-GAAP operating expenses for 2026

Result Drivers

  • PRODUCT LAUNCHES - TRYNGOLZA sales increased 56% QoQ, driven by successful launch and EU approval

  • R&D REVENUE - $280 mln upfront payment from Ono Pharmaceutical for sapablursen licensing boosted revenue

  • EXPENSES - Increased operating expenses due to commercialization efforts for TRYNGOLZA, DAWNZERA and WAINUA

Company press release: ID:nBw2nfT4Ba

Key Details

Metric

Beat/Miss

Actual

Consensus Estimate

Q4 Revenue

Beat

$203 mln

$156.09 mln (15 Analysts)

Q4 Adjusted Operating Income

Beat

-$172 mln

-$210.27 mln (13 Analysts)

Q4 Adjusted Operating Expenses

$375 mln

Q4 Operating Expenses

$418 mln

Q4 Operating Income

-$215 mln

Analyst Coverage

  • The current average analyst rating on the shares is "buy" and the breakdown of recommendations is 17 "strong buy" or "buy", 6 "hold" and no "sell" or "strong sell"

  • The average consensus recommendation for the biotechnology & medical research peer group is "buy"

  • Wall Street's median 12-month price target for Ionis Pharmaceuticals Inc is $95.00, about 11.2% above its February 24 closing price of $85.45

For questions concerning the data in this report, contact Estimates.Support@lseg.com. For any other questions or feedback, contact reuters.support@thomsonreuters.com.

(This story was created using Reuters automation and AI based on LSEG and company data. It was checked and edited by a Reuters journalist prior to publication.)

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