Innovent Biologics Inc. said China’s National Medical Products Administration has approved Jaypirca (pirtobrutinib), a non-covalent BTK inhibitor, for adult patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma who have received at least one prior systemic therapy including a BTK inhibitor. The company said the approval was supported by results from the Phase 3 BRUIN CLL-321 trial comparing pirtobrutinib with investigator’s choice regimens. Innovent said pirtobrutinib is developed by Eli Lilly and Company and commercialized in mainland China by Innovent.
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