Jasper Therapeutics Inc. highlighted progress for briquilimab, an investigational anti-KIT antibody designed to deplete mast cells, with clinical data reported in more than 95 patients across studies in chronic spontaneous urticaria, chronic inducible urticaria and asthma. The company said chronic urticaria studies showed rapid reductions in UAS7 and complete responses observed as early as week 2 in multiple cohorts, and noted asthma proof-of-concept findings that included FEV1 improvement and substantial reductions in eosinophils. Jasper outlined upcoming development plans, including a Phase 2b registrational study in chronic spontaneous urticaria targeted to start in the second half of 2026 and a Phase 3 study in chronic inducible urticaria planned to commence in early 2028. You can access the full presentation through the link below.
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