C4 Therapeutics Inc. released a corporate presentation outlining its targeted protein degradation portfolio and development plans. The company highlighted two clinical programs: cemsidomide, an IKZF1/3 degrader for multiple myeloma, and CFT8919, an EGFR L858R degrader for non-small cell lung cancer. The presentation describes planned clinical milestones for cemsidomide, including the Phase 2 MOMENTUM trial in fourth-line or later multiple myeloma and a Phase 1b combination study with Pfizer-supplied elranatamab, as well as a discovery strategy focused on inflammation, neuroinflammation and neurodegeneration targets. You can access the full presentation through the link below.
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