Nuvation Bio Inc. highlighted its oncology portfolio, including IBTROZI (taletrectinib), a ROS1 inhibitor approved in the U.S., Japan and China for advanced ROS1-positive non-small cell lung cancer. The company reported 2025 U.S. net product revenue of $24.7 million and 432 new patient starts since launch, and said it is enrolling the TRUST-IV study in early-stage ROS1-positive NSCLC. The presentation also outlined development of safusidenib, an IDH1 inhibitor being evaluated in the pivotal SIGMA study for high-risk or high-grade IDH1-mutant astrocytoma, alongside a non-pivotal cohort for grade 3 IDH1-mutant oligodendroglioma. Nuvation Bio also described ongoing evaluation of preclinical candidates from its Drug-Drug Conjugate platform and reported a pro forma cash balance of approximately $589 million. You can access the full presentation through the link below.
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