Incannex to Launch DReAMzz Phase 2 Crossover Dose-Optimization Study for IHL-42X and Advance a Streamlined Phase 3 Program Toward Potential Registration in Obstructive Sleep Apnea

Reuters03-12
Incannex to Launch DReAMzz Phase 2 Crossover Dose-Optimization Study for IHL-42X and Advance a Streamlined Phase 3 Program Toward Potential Registration in Obstructive Sleep Apnea

Incannex Healthcare Inc. announced an updated clinical development plan for its obstructive sleep apnea candidate IHL-42X that includes initiating a Phase 2 crossover dose-optimization study (DReAMzz) to test multiple ratios of dronabinol and acetazolamide and select an optimal formulation. The company said it has appointed a contract research organization and expects to begin dosing patients in the coming months. Incannex plans to use results from DReAMzz to support a streamlined Phase 3 program, potentially run under a single master protocol with parallel studies, with the goal of optimizing efficacy, maintaining safety, and supporting a more efficient pathway toward potential registration.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Incannex Healthcare Inc. published the original content used to generate this news brief on March 12, 2026, and is solely responsible for the information contained therein.

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