Terns Pharmaceuticals publishes corporate presentation on TERN-701 oral allosteric BCR-ABL inhibitor for CML with 75% MMR at 24 weeks

Reuters03-10

Terns Pharmaceuticals publishes corporate presentation on TERN-701 oral allosteric BCR-ABL inhibitor for CML with 75% MMR at 24 weeks

Terns highlighted TERN-701, an oral allosteric BCR-ABL inhibitor being studied for chronic myeloid leukemia, and cited a 75% major molecular response rate by 24 weeks at doses of at least 320 mg once daily. The company said the Phase 1 CARDINAL study enrolled 63 patients as of a September 2025 data cutoff, including 38% previously treated with asciminib. Terns reported no dose-limiting toxicities and said maximum tolerated dose was not identified, while treatment-emergent adverse events of grade 3 or higher occurred in 32% of patients. The presentation also cited a cash balance of about USD 1 billion and about 115 million shares outstanding, which it said supports runway into 2031 including a potential first approval and commercial launch of TERN-701.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Terns Pharmaceuticals Inc. published the original content used to generate this news brief on March 09, 2026, and is solely responsible for the information contained therein.

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