TransThera doses first patient in China Phase II trial of tinengotinib plus fulvestrant for HR+/HER2- metastatic breast cancer

Reuters03-18

TransThera doses first patient in China Phase II trial of tinengotinib plus fulvestrant for HR+/HER2- metastatic breast cancer

TransThera said the first patient has been dosed in a China-based, open-label, multicenter phase II trial of tinengotinib (TT-00420) in combination with fulvestrant for previously treated HR+/HER2- relapsed or metastatic breast cancer. The study will evaluate safety, efficacy, and pharmacokinetics in patients who previously received endocrine therapy and a CDK4/6 inhibitor. The announcement did not report clinical results, and no timing for future data presentation was provided.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Transthera Sciences (Nanjing) Inc. published the original content used to generate this news brief via IIS, the Issuer Information Service operated by the Hong Kong Stock Exchange (HKex) (Ref. ID: HKEX-EPS-20260318-12057757), on March 18, 2026, and is solely responsible for the information contained therein.

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