Moderna reported progress in shifting its commercial focus to mNEXSPIKE, which launched in Q3 2025 and became its leading product in the U.S. retail channel. The company said it had three commercial respiratory products, including Spikevax and mRESVIA, and total 2025 revenue of USD 1.9 billion largely from COVID vaccine sales. Moderna said regulatory reviews were ongoing for its flu plus COVID combination vaccine candidate mRNA-1083 in Europe and Canada, and its flu vaccine candidate mRNA-1010 with an FDA PDUFA goal date of Aug. 5, 2026. In oncology, Moderna and Merck reported five-year Phase 2b data for intismeran autogene (mRNA-4157) with pembrolizumab, and said eight Phase 2 and Phase 3 trials are underway across tumor types. Moderna said it expanded its manufacturing network in 2025 with new U.S. drug product capabilities and added Moderna-built facilities in the UK, Canada and Australia, while its Marlborough, Massachusetts site began clinical batch supply for intismeran in September 2025.
Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Moderna Inc. published the original content used to generate this news brief on March 16, 2026, and is solely responsible for the information contained therein.
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