Volition reported an updated manuscript describing a two-step method that generated sequencing datasets with more than 99% purity for circulating tumor-derived DNA from blood samples of cancer patients. The manuscript includes proof-of-concept and early blinded validation results that reported 49 of 49 cancers detected in one cohort and 13 of 14 later-stage cancers detected in a second blinded cohort. The company said it is working on an additional validation cohort focused on early-stage cancers, with results expected in the future. Volition also cited a total addressable market estimate of about USD 23 billion for multi-cancer early detection and more than USD 13 billion for minimal residual disease.
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