Anavex reports 77.4-week time saved with oral blarcamesine in AD-004 early Alzheimer’s trial after 144 weeks of treatment

Reuters03-23
Anavex reports 77.4-week time saved with oral blarcamesine in AD-004 early Alzheimer’s trial after 144 weeks of treatment
  • Anavex reported new analyses from the ANAVEX 2-73-AD-004 Phase IIb/III program and its ANAVEX 2-73-AD-EP-004 open-label extension in early Alzheimer’s disease, and said the results were presented at the AD/PD 2026 conference.
  • MRI biomarker analyses showed a correlation between slowing of brain atrophy and changes on ADAS-Cog13, ADCS-ADL, and CDR-SB.
  • In the ABCLEAR3 precision-medicine subgroup, the reported R² for the relationship between atrophy slowing and ADAS-Cog13 increased from 0.23 to 0.41.
  • Long-term data cited by Anavex indicated 77.4 weeks of “time saved” versus an ADNI control group after 144 weeks of treatment.


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