Tonix Pharmaceuticals dosed first participant in Phase 1 TNX-1900 intranasal oxytocin study; trial measures trigeminal neurovascular reactivity in healthy female volunteers

Reuters03-26
Tonix Pharmaceuticals dosed first participant in Phase 1 TNX-1900 intranasal oxytocin study; trial measures trigeminal neurovascular reactivity in healthy female volunteers
  • Tonix reported that the first participant was dosed in a Phase 1 investigator-initiated pharmacodynamic study of TNX-1900, an intranasal potentiated oxytocin drug-device combination being evaluated for potential use in migraine and craniofacial pain.
  • The study will assess trigeminal nerve-mediated forehead vasodilation by measuring skin blood flow responses to capsaicin and electrical stimulation using Laser Speckle Contrast Imaging.
  • No clinical results were presented, and the company said results from the study will be used to guide future development of TNX-1900.


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