Innovent partner Ollin says OLN324 beats Roche’s Vabysmo on DME anatomy in Phase 1b trial

Reuters03-31
Innovent partner Ollin says OLN324 beats Roche’s Vabysmo on DME anatomy in Phase 1b trial
  • Innovent partner Ollin Biosciences released final 20-week data from Phase 1b JADE head-to-head study of OLN324 (IBI324) versus Roche’s Vabysmo in diabetic macular edema or wet age-related macular degeneration.
  • Results showed OLN324 delivered stronger anatomic improvements in diabetic macular edema, with vision gains that held up through follow-up.
  • Wet age-related macular degeneration data showed comparable fluid control, with a widening edge in vision outcomes for OLN324 by study end.
  • Newly available anatomic analyses indicated faster, greater, more durable reductions in pigment epithelial detachments versus Vabysmo.
  • Full data set is expected to be presented at upcoming medical meetings, with global Phase 3 studies planned for 2026.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Innovent Biologics Inc. published the original content used to generate this news brief via PR Newswire (Ref. ID: 202603302000PR_NEWS_USPR_____CN20962) on March 31, 2026, and is solely responsible for the information contained therein.

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