Novartis says Fabhalta slows kidney function decline 49.3% in Phase III IgAN trial

Reuters13:16

Novartis says Fabhalta slows kidney function decline 49.3% in Phase III IgAN trial

Novartis reported final two-year Phase III APPLAUSE-IgAN results showing Fabhalta (iptacopan) slowed eGFR decline by 49.3% versus placebo.
Data were published in New England Journal of Medicine.
Results were presented as late-breaking data at 2026 World Congress of Nephrology.
Trial showed 43% lower likelihood of progression to kidney failure events, with HR 0.57.
Novartis said FDA granted priority review for traditional approval in IgA nephropathy.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Novartis AG published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 202603290115OMX_____CNEWS_EN_GNW1001172693_en) on March 29, 2026, and is solely responsible for the information contained therein.

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