Corcept MOMENTUM trial finds hypercortisolism in 27.3% of resistant hypertension patients

Reuters03-29
Corcept MOMENTUM trial finds hypercortisolism in 27.3% of resistant hypertension patients
  • Corcept presented late-breaking MOMENTUM trial data at ACC 2026 on endogenous hypercortisolism prevalence in resistant hypertension.
  • Screening of 1,086 patients found 27.3% had hypercortisolism.
  • Results extend Corcept’s earlier CATALYST screening study in difficult-to-control type 2 diabetes, which found 23.8% prevalence in 1,057 patients.
  • High-risk subgroup with HbA1c ≥7.5% on three or more blood pressure medicines showed 32.6% prevalence in MOMENTUM.
  • Data support broader screening for hypercortisolism in hard-to-treat cardiometabolic patients, potentially expanding diagnosis rates relevant to Corcept’s cortisol-modulating drug portfolio.


Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Corcept Therapeutics Incorporated published the original content used to generate this news brief via Business Wire (Ref. ID: 20260328971109) on March 28, 2026, and is solely responsible for the information contained therein.

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