Nanjing Leads Biolabs’ LBL-024 Phase II biliary tract cancer trial enters expansion phase

Reuters04-08 16:33
Nanjing Leads Biolabs’ LBL-024 Phase II biliary tract cancer trial enters expansion phase
  • Nanjing Leads Biolabs reported Phase II study of Opamtistomig (LBL-024), its PD-L1/4-1BB bispecific antibody, for first-line advanced biliary tract cancer has moved into expansion phase.
  • Safety run-in phase completed preliminary assessment in 20 patients, supporting continuation on tolerability.
  • Early efficacy readout showed an encouraging trend in tumor shrinkage, without disclosing detailed response figures.
  • First patient has been enrolled in expansion phase as trial accelerates across multiple hospitals in China.
  • Results have been presented as preliminary findings from safety run-in phase, with expansion-phase data expected in future updates.


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