BioNTech Phase 2 endometrial cancer trial shows 48% response for trastuzumab pamirtecan

Reuters04-11 19:00

BioNTech Phase 2 endometrial cancer trial shows 48% response for trastuzumab pamirtecan

BioNTech reported positive Phase 2 results for investigational HER2-targeted antibody-drug conjugate trastuzumab pamirtecan in heavily pretreated patients with HER2-expressing recurrent endometrial cancer.
Data were presented in an oral session at 2026 Society of Gynecologic Oncology Annual Meeting on Women’s Cancers.
Study met primary efficacy endpoint, showing clinically meaningful tumor responses across HER2 expression levels with manageable safety.
BioNTech is running confirmatory Phase 3 trial Fern-EC-01 to support a planned US biologics license application filing in 2026, subject to FDA feedback.

Disclaimer: This news brief was created by Public Technologies (PUBT) using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. BioNTech SE published the original content used to generate this news brief via GlobeNewswire (Ref. ID: 202604110700OMX_____CNEWS_EN_GNW1001175275_en) on April 11, 2026, and is solely responsible for the information contained therein.

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