AtaiBeckley's lead asset, BPL-003, has initiated Phase three activities for treatment-resistant depression after receiving Breakthrough Therapy Designation from the FDA. The compound is a synthetic form of 5-MeO-DMT administered intranasally. In a Phase 2b study, BPL-003 demonstrated rapid and durable reductions in depressive symptoms following an in-clinic visit lasting approximately two hours on average, with effects persisting for months. The program targets patients whose depression hasn't responded to multiple treatments. VLS-01, a buccal film formulation of DMT, is also advancing in an ongoing Phase 2b study
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(END) Dow Jones Newswires
July 16, 2026 07:07 ET (11:07 GMT)
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