AKESO(09926),Stock Price, Discussion, News, Quote & History - To The Moon - Tiger Brokers Online Investing Community - To The Moon

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09926 AKESO

Closed 12-08 16:08:10

124.400

+0.300

+0.24%

High128.600	Low122.300	Vol6.76M
Open127.400	D1 Closing124.100	Amplitude5.08%
Mkt Cap114.57B	Tradable Cap114.57B	Total Shares921.00M
T/O841.55M	T/O Rate0.73%	Tradable Shares921.00M
P/B--	ROE--	EPS0.00
52wk High--	52wk Low--	P/E--
Dividend--	Div.Yield--	ROA--

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While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Akeso Inc. published the original content used to generate this news brief via PR Newswire  on December 07, 2025, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251207:nNDL4V3wLM:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B543WZ88.USD","LU0348827113.USD","LU1720050803.USD","09926","BK1574","LU0348825331.USD","LU0348766576.USD","LU2476274720.SGD","LU1794554557.SGD","LU0417516738.SGD","LU2778985437.USD","LU0540923850.HKD","IE00B5MMRT66.SGD","LU0348783233.USD","LU0348784397.USD","LU2476274308.USD","LU2399975544.HKD","LU0634319403.HKD","BK1161","LU0561508036.HKD","LU2488822045.USD","BK4185","IE00BPRC5H50.USD","NHC","LU0348735423.USD","LU0417516571.SGD","LU1961090484.USD","LU0417516902.SGD","LU0348767384.USD"],"gpt_icon":0},{"id":"1146416783","title":"Akeso, Inc. 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According to the announcement, the company’s authorized share capital remains at 5,000,000,000...","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport,SGX","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["09926"],"gpt_icon":0},{"id":"1134728285","title":"10th Zhitong Capital Market Annual Conference Honors Excellence with 25 Awards Unveiled","url":"https://stock-news.laohu8.com/highlight/detail?id=1134728285","media":"Stock News","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1134728285?lang=en_us&edition=fundamental","pubTime":"2025-12-03 19:38","pubTimestamp":1764761917,"startTime":"0","endTime":"0","summary":"On December 3, 2025, the \"10th Zhitong Capital Market 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Akeso’s (SEHK:9926) First Alzheimer’s Bispecific Antibody Approval Reinvent Its Innovation Narrative?","url":"https://stock-news.laohu8.com/highlight/detail?id=2586420978","media":"Simply Wall St.","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2586420978?lang=en_us&edition=fundamental","pubTime":"2025-11-25 16:15","pubTimestamp":1764058503,"startTime":"0","endTime":"0","summary":"Earlier this month, Akeso, Inc. announced that its novel bispecific antibody AK152 received approval from the National Medical Products Administration (NMPA) to begin clinical trials for Alzheimer's Disease, marking the first such therapy of its kind developed in China for disease modification. \nThis milestone also signifies Akeso's entry into innovative central nervous system therapeutics, leveraging enhanced brain penetration and robust preclinical results for potential next-generation...","market":"hk","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-9926/akeso-shares/news/does-akesos-sehk9926-first-alzheimers-bispecific-antibody-ap","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-9926/akeso-shares/news/does-akesos-sehk9926-first-alzheimers-bispecific-antibody-ap","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["LU0561508036.HKD","LU0348766576.USD","LU2399975544.HKD","LU0634319403.HKD","LU2488822045.USD","LU2476274308.USD","LU0348767384.USD","LU0348783233.USD","09926","LU2778985437.USD","LU0348825331.USD","IE00BPRC5H50.USD","LU0348735423.USD","LU0417516902.SGD","LU2476274720.SGD","LU0348827113.USD","LU0348784397.USD","BK1574","LU1961090484.USD","IE00B543WZ88.USD","LU0417516738.SGD","LU0540923850.HKD","LU1794554557.SGD","LU1720050803.USD","LU0417516571.SGD","IE00B5MMRT66.SGD","BK1161"],"gpt_icon":0},{"id":"2585197407","title":"Akeso (SEHK:9926) Valuation: Assessing Pipeline Momentum After Landmark Alzheimer’s and Oncology R&D Milestones","url":"https://stock-news.laohu8.com/highlight/detail?id=2585197407","media":"Simply Wall St.","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2585197407?lang=en_us&edition=fundamental","pubTime":"2025-11-21 11:26","pubTimestamp":1763695588,"startTime":"0","endTime":"0","summary":"Akeso (SEHK:9926) has just been cleared by China’s National Medical Products Administration to initiate clinical trials for AK152, its first bispecific antibody aimed at tackling Alzheimer’s Disease, and a breakthrough in the domestic biotech space.\nSee our latest analysis for Akeso.\nWhile Akeso's progress on Alzheimer's and its oncology advances have kept it in the headlines, the share price has pulled back 36% over the past three months after a rapid rally earlier this year. Still, the...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-9926/akeso-shares/news/akeso-sehk9926-valuation-assessing-pipeline-momentum-after-l","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-9926/akeso-shares/news/akeso-sehk9926-valuation-assessing-pipeline-momentum-after-l","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["LU0348827113.USD","BK4533","LU2488822045.USD","LU0868494617.USD","SG9999002224.SGD","LU1961090484.USD","LU2476274720.SGD","BK4588","BK4534","IE0002270589.USD","IE00B543WZ88.USD","LU1023059063.AUD","BK4211","IE00B19Z3581.USD","LU0289739699.SGD","LU0306807586.USD","IE00B19Z3B42.SGD","LU0561508036.HKD","LU0348735423.USD","LU1066051498.USD","LU1894683348.USD","LARK","BK4550","LU0634319403.HKD","LU1057294990.SGD","LU0321505868.SGD","BK1161","LU1883839398.USD","LU1720050803.USD","SG9999011175.SGD","SGXZ57979304.SGD","SG9999001176.SGD","LU0348825331.USD","09926","LU0348766576.USD","LU2778985437.USD","IE00BPRC5H50.USD","LU0417516571.SGD","IE00B5MMRT66.SGD","IE00BBT3K403.USD","LU0348767384.USD","LU0321505439.SGD","BK4585","LU0540923850.HKD","LU2399975544.HKD","IE000M9KFDE8.USD","SG9999013999.USD","BK1574","LU0348783233.USD"],"gpt_icon":1},{"id":"2584349618","title":"Akeso Wins China Approval to Begin Clinical Trials of Bispecific Antibody for Alzheimer's","url":"https://stock-news.laohu8.com/highlight/detail?id=2584349618","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2584349618?lang=en_us&edition=fundamental","pubTime":"2025-11-17 10:29","pubTimestamp":1763346595,"startTime":"0","endTime":"0","summary":"Akeso Inc. has received regulatory approval from China's National Medical Products Administration  to initiate clinical trials for AK152, a novel bispecific antibody targeting both amyloid-beta (Aβ) and a blood-brain barrier  expressed receptor for the treatment of Alzheimer's Disease. AK152 is the first bispecific antibody developed in China for this indication, marking a significant advancement in disease-modifying therapy for Alzheimer's. The approval allows Akeso to begin clinical studies, following promising preclinical results demonstrating robust bioactivity, improved brain penetration, and accelerated clearance of Aβ plaques. No other organizations were mentioned as recipients of this approval.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. 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Securities: Rates AKESO (09926) as \"Buy\" on Strong Efficacy and Broad Market Potential of Innovative Drugs","url":"https://stock-news.laohu8.com/highlight/detail?id=1151848502","media":"Stock News","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1151848502?lang=en_us&edition=fundamental","pubTime":"2025-11-13 16:50","pubTimestamp":1763023857,"startTime":"0","endTime":"0","summary":"CITIC Securities released a research report highlighting AKESO's (09926) robust R&D pipeline, with multiple investigational products and indications nearing approval. The company continues to expand...","market":"fut","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1794554557.SGD","LU0348827113.USD","LU0540923850.HKD","LU0561508036.HKD","LU2476274720.SGD","BK1574","09926","LU2399975544.HKD","LU1961090484.USD","06978","LU0417516738.SGD","LU2488822045.USD","LU2778985437.USD","LU0348735423.USD","LU0417516902.SGD","LU0348784397.USD","IE00B543WZ88.USD","LU0348766576.USD","LU0348767384.USD","BK1161","LU0634319403.HKD","IE00B5MMRT66.SGD","IE00BPRC5H50.USD","LU0417516571.SGD","LU1720050803.USD","LU0348825331.USD","159992","LU2476274308.USD","LU0348783233.USD"],"gpt_icon":0},{"id":"2583373505","title":"The Bull Case For Akeso (SEHK:9926) Could Change Following New Oncology Pipeline Milestones and Clinical Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2583373505","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2583373505?lang=en_us&edition=fundamental","pubTime":"2025-11-13 12:49","pubTimestamp":1763009381,"startTime":"0","endTime":"0","summary":"In early November 2025, Akeso announced a series of pipeline milestones, including the first patient dosing in a Phase I trial of its mRNA vaccine AK154, the presentation of promising Overall Survival results for ivonescimab in EGFR-mutated non-small cell lung cancer at SITC, and new preclinical data for its novel antibody AK135.\nThe rapid progress across both late-stage and innovative early-stage assets underscores Akeso's efforts to expand its oncology portfolio while solidifying its...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice1-main-header/1585186710114"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-9926/akeso-shares/news/the-bull-case-for-akeso-sehk9926-could-change-following-new","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/hk/pharmaceuticals-biotech/hkg-9926/akeso-shares/news/the-bull-case-for-akeso-sehk9926-could-change-following-new","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["LU2488822045.USD","LU1961090484.USD","LU0417516571.SGD","IE00B5MMRT66.SGD","LU0634319403.HKD","BK1574","LU0348784397.USD","LU2399975544.HKD","LU2778985437.USD","LU0348783233.USD","LU0417516902.SGD","LU0348766576.USD","IE00B543WZ88.USD","LU0348735423.USD","LU0348827113.USD","LU1794554557.SGD","LU0540923850.HKD","LU0348825331.USD","LU1720050803.USD","LU0561508036.HKD","BK1161","LU0417516738.SGD","LU2476274720.SGD","09926","LU0348767384.USD","IE00BPRC5H50.USD","LU2476274308.USD"],"gpt_icon":0},{"id":"1112478778","title":"HK Movers | Innovative Drug Stocks Jump With Ascletis Pharma and BeOne Medicines up 6%","url":"https://stock-news.laohu8.com/highlight/detail?id=1112478778","media":"Tiger Newspress","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1112478778?lang=en_us&edition=fundamental","pubTime":"2025-11-12 10:00","pubTimestamp":1762912816,"startTime":"0","endTime":"0","summary":"Innovative drug stocks jumped in Hong Kong. Ascletis Pharma and BeOne Medicines rose 6%; Akeso rose 4%; Jinxin Fertility rose 2%.","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"93ca2ea8f560905425dc4dda4a045e37","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["01951","09926","01672","06160"],"gpt_icon":0},{"id":"1172850038","title":"HK Stock Movement | AKESO (09926) Rises Nearly 5% as Phase I Clinical Trial of AK154 Monotherapy or Combined with Cadonilimab/Ivonescimab Completes First Dosing for Pancreatic Cancer Adjuvant Therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=1172850038","media":"Stock News","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1172850038?lang=en_us&edition=fundamental","pubTime":"2025-11-12 10:00","pubTimestamp":1762912815,"startTime":"0","endTime":"0","summary":"AKESO (09926) surged nearly 5%, reaching HK$119.9 by the time of writing, with a trading volume of HK$310 million. The company announced via its official WeChat account that the first patient has...","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0348827113.USD","LU0348735423.USD","LU0348767384.USD","LU1794554557.SGD","LU2488822045.USD","LU2778985437.USD","LU0540923850.HKD","LU0417516571.SGD","LU1720050803.USD","BK1161","LU2476274720.SGD","LU0348766576.USD","LU0561508036.HKD","LU2399975544.HKD","LU0417516738.SGD","LU0348783233.USD","BK1574","LU0348784397.USD","LU1961090484.USD","IE00B5MMRT66.SGD","IE00B543WZ88.USD","09926","LU0417516902.SGD","IE00BPRC5H50.USD","LU0348825331.USD","LU2476274308.USD","LU0634319403.HKD"],"gpt_icon":0},{"id":"2582878522","title":"Akeso Begins Phase I Trial of Personalized mRNA Vaccine AK154 for Pancreatic Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2582878522","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582878522?lang=en_us&edition=fundamental","pubTime":"2025-11-10 19:40","pubTimestamp":1762774805,"startTime":"0","endTime":"0","summary":"Akeso Inc. has announced that the first patient has been dosed in a Phase I clinical trial of its personalized mRNA vaccine candidate AK154 for the adjuvant treatment of pancreatic cancer. The study will evaluate AK154 as a monotherapy and in combination with Akeso's bispecific antibodies, cadonilimab  and ivonescimab , following surgical resection. AK154 is Akeso's first mRNA-based therapeutic candidate to enter clinical development. According to the company, preclinical data showed strong immunogenicity, potent anti-tumor activity, and a favorable safety profile. Clinical results from this trial have not yet been presented.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Akeso Inc. published the original content used to generate this ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nNDL7K36gv:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0417516902.SGD","LU0348827113.USD","LU2488822045.USD","LU1961090484.USD","LU0417516738.SGD","LU2476274720.SGD","IE00B543WZ88.USD","LU0561508036.HKD","LU0348735423.USD","LU0634319403.HKD","BK1161","LU1720050803.USD","LU0348784397.USD","LU0348825331.USD","09926","LU0348766576.USD","LU2778985437.USD","IE00BPRC5H50.USD","LU0417516571.SGD","LU1794554557.SGD","LU2476274308.USD","IE00B5MMRT66.SGD","LU0348767384.USD","LU0540923850.HKD","LU2399975544.HKD","BK1574","LU0348783233.USD"],"gpt_icon":0},{"id":"2582878396","title":"Akeso Announces First Patient Dosed in Phase I Trial of Personalized Mrna Vaccine Ak154 as Monotherapy or in Combination With Cadonilimab or Ivonescimab for Adjuvant Treatment of Pancreatic Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2582878396","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582878396?lang=en_us&edition=fundamental","pubTime":"2025-11-10 19:39","pubTimestamp":1762774775,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nTUABFNNG3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LU0417516571.SGD","IE00B5MMRT66.SGD","LU1720050803.USD","LU2778985437.USD","LU0417516902.SGD","LU1794554557.SGD","IE00B543WZ88.USD","LU0348784397.USD","LU2488822045.USD","LU0348766576.USD","LU0540923850.HKD","BK1574","LU0634319403.HKD","LU2476274720.SGD","LU0561508036.HKD","BK1161","LU0417516738.SGD","LU2476274308.USD","LU0348767384.USD","LU0348825331.USD","LU2399975544.HKD","09926","LU0348783233.USD","LU0348827113.USD","IE00BPRC5H50.USD","LU1961090484.USD","LU0348735423.USD"],"gpt_icon":0},{"id":"2581188717","title":"Akeso Inc. Wins China Approval for Ivonescimab in EGFR-Mutated NSCLC","url":"https://stock-news.laohu8.com/highlight/detail?id=2581188717","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581188717?lang=en_us&edition=fundamental","pubTime":"2025-11-08 00:30","pubTimestamp":1762533030,"startTime":"0","endTime":"0","summary":"Akeso Inc. announced that ivonescimab, its novel therapy for EGFR-mutated non-squamous non-small cell lung cancer  following EGFR-TKI progression, received regulatory approval from the China National Medical Products Administration in May 2024. The drug was subsequently added to China's National Reimbursement Drug List  in November 2024, ensuring broad patient access starting January 1, 2025. Additionally, Akeso's global partner, Summit Therapeutics, plans to submit a Biologics License Application  to the U.S. FDA in the fourth quarter of 2025 for the same indication.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Akeso Inc. published the original content used to generate this news brief via PR Newswire  on November 07, 2025, and is so","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251107:nNDL4vjRW0:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK1161","LU2399975544.HKD","LU0561508036.HKD","SMMT","BK4139","LU0634319403.HKD","09926","IE00B5MMRT66.SGD","LU0417516738.SGD","IE00B543WZ88.USD","LU2476274308.USD","LU0348827113.USD","LU2488822045.USD","LU0348735423.USD","LU0348767384.USD","LU0348825331.USD","BK1574","LU2476274720.SGD","LU0417516571.SGD","LU1720050803.USD","LU1961090484.USD","LU0348783233.USD","IE00BPRC5H50.USD","LU1794554557.SGD","LU2778985437.USD","LU0540923850.HKD","LU0348784397.USD","LU0417516902.SGD","LU0348766576.USD"],"gpt_icon":0},{"id":"2581887170","title":"Akeso Reports AK135 Antibody Blocks Key Inflammatory Pathways and Relieves Neuropathy Pain in Preclinical Studies","url":"https://stock-news.laohu8.com/highlight/detail?id=2581887170","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581887170?lang=en_us&edition=fundamental","pubTime":"2025-11-08 00:30","pubTimestamp":1762533023,"startTime":"0","endTime":"0","summary":"Akeso Inc. has announced promising preclinical research results for its novel monoclonal antibody, AK135, which targets the IL-1 receptor accessory protein . The results were presented at the 40th Annual Meeting of the Society for Immunotherapy of Cancer  in 2025. AK135 demonstrated high affinity for IL-1RAP and effectively blocked the IL-1, IL-33, and IL-36 pro-inflammatory signaling pathways in vitro, leading to reduced secretion of inflammatory cytokines. In animal models of chemotherapy-induced peripheral neuropathy, AK135 provided significant, dose-dependent pain relief without notable toxicity. These findings suggest AK135 could offer a new treatment option for neuropathic pain in cancer patients.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251107:nNDL7b1RHD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1720050803.USD","LU2399975544.HKD","LU0348783233.USD","BK1161","LU0348767384.USD","LU2476274720.SGD","LU0540923850.HKD","LU0348825331.USD","LU0348827113.USD","09926","LU0417516571.SGD","LU0417516738.SGD","IE00B543WZ88.USD","IE00B5MMRT66.SGD","LU1961090484.USD","LU0348766576.USD","IE00BPRC5H50.USD","LU2778985437.USD","LU0634319403.HKD","LU0348784397.USD","LU2488822045.USD","LU1794554557.SGD","BK1574","LU0348735423.USD","LU0561508036.HKD","LU0417516902.SGD","LU2476274308.USD"],"gpt_icon":0},{"id":"2581886538","title":"Summit Therapeutics Reports Ivonescimab Plus Chemotherapy Improves Survival in EGFR-Mutated NSCLC Phase III Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2581886538","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581886538?lang=en_us&edition=fundamental","pubTime":"2025-11-07 22:01","pubTimestamp":1762524068,"startTime":"0","endTime":"0","summary":"Summit Therapeutics Inc. announced that results from the Phase III HARMONi-A clinical trial, conducted by its partner Akeso, Inc. in China, have been presented at the Annual Meeting of the Society for Immunotherapy of Cancer . The trial evaluated the investigational bispecific antibody ivonescimab in combination with chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous non-small cell lung cancer  who had previously received a third-generation EGFR TKI. The study demonstrated a statistically significant benefit in overall survival, with a reported hazard ratio of 0.74. The safety profile of ivonescimab in combination with chemotherapy was described as manageable. In May 2024, Akeso announced the approval of ivonescimab plus chemotherapy in this treatment setting in China, following the HARMONi-A trial results. An administrative review of overall survival at 52% data maturity reported a hazard ratio of 0.80  with a data cutoff in December 2023.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251107:nNDL8MRSy6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1720050803.USD","BK4139","LU2399975544.HKD","LU0348783233.USD","BK1161","LU0348767384.USD","LU2476274720.SGD","LU0540923850.HKD","LU0348825331.USD","LU0348827113.USD","09926","LU0417516571.SGD","SMMT","LU0417516738.SGD","IE00B543WZ88.USD","IE00B5MMRT66.SGD","LU1961090484.USD","LU0348766576.USD","IE00BPRC5H50.USD","LU2778985437.USD","LU0634319403.HKD","LU0348784397.USD","LU2488822045.USD","LU1794554557.SGD","BK1574","LU0348735423.USD","LU0561508036.HKD","LU0417516902.SGD","LU2476274308.USD"],"gpt_icon":0}],"profile":{"websiteUrl":"http://www.akesobio.com","stockEarnings":[{"period":"1week","weight":0.0098},{"period":"1month","weight":0.0886},{"period":"3month","weight":-0.1978},{"period":"6month","weight":0.5088},{"period":"1year","weight":0.8961},{"period":"ytd","weight":1.0445}],"compareEarnings":[{"period":"1week","weight":0.0087},{"period":"1month","weight":0.0058},{"period":"3month","weight":0.0262},{"period":"6month","weight":0.0964},{"period":"1year","weight":0.3336},{"period":"ytd","weight":0.3004}],"compareStock":{"symbol":"HSI","name":"HSI"},"description":"Akeso Inc is an investment holding company dedicated to the research, development, manufacturing and commercialization of antibody drugs that are affordable to patients worldwide. The Company’s programs covering the therapeutic areas of oncology, autoimmune and metabolic diseases. The Company's products mainly include cadonilimab (PD-1/CTLA-4), ivonescimab (PD-1/VEGF), Ligufalimab (AK117, CD47), Pulocimab (AK109, VEGFR-2), ANNIKO (penpulimab, PD-1), and tagitanlimab (PD-L1) used in oncology fields as well as ebronucimab (PCSK9), ebdarokimab (IL-12/IL-23), and Gumokimab (AK111, IL-17) used in metabolic and autoimmune therapeutic fields.","yearOnYearQuotes":[{"month":1,"riseRate":0.6,"avgChangeRate":0.000596},{"month":2,"riseRate":0.4,"avgChangeRate":0.029178},{"month":3,"riseRate":0.4,"avgChangeRate":-0.035342},{"month":4,"riseRate":0.8,"avgChangeRate":0.041218},{"month":5,"riseRate":0.333333,"avgChangeRate":-0.003133},{"month":6,"riseRate":0.666667,"avgChangeRate":0.133235},{"month":7,"riseRate":0.5,"avgChangeRate":0.087867},{"month":8,"riseRate":0.5,"avgChangeRate":-0.007754},{"month":9,"riseRate":0.5,"avgChangeRate":0.036209},{"month":10,"riseRate":0.5,"avgChangeRate":0.046029},{"month":11,"riseRate":1,"avgChangeRate":0.102206},{"month":12,"riseRate":0.5,"avgChangeRate":0.043332}],"exchange":"SEHK","name":"AKESO","nameEN":"AKESO"},"APP":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isDev":false,"isTTM":true,"deviceId":"web-server-community-laohu8-v3","version":"4.35.10","shortVersion":"4.35.10","platform":"web","vendor":"web","appName":"ttm","isIOS":false,"isAndroid":false,"isTiger":false,"isTHS":false,"isWeiXin":false,"isWeiXinMini":false,"isWeiBo":false,"isQQ":false,"isBaiduSwan":false,"isBaiduBox":false,"isDingTalk":false,"isToutiao":false,"isOnePlus":false,"isHuaWei":false,"isXiaomi":false,"isXiaomiWebView":false,"isOppo":false,"isVivo":false,"isSamsung":false,"isMobile":false},"pagemeta":{"title":"AKESO(09926),Stock Price, Discussion, News, Quote & History - To The Moon - Tiger Brokers Online Investing Community","description":"Find the latest AKESO(09926) stock quote, history, news, and investing ideas from To The Moon - Tiger Brokers Online Investing Community to stay on top of the markets.","keywords":"AKESO,09926,AKESO股票,AKESO股票老虎,AKESO股票老虎国际,AKESO行情,AKESO股票行情,AKESO股价,AKESO股市,AKESO股票价格,AKESO股票交易,AKESO股票购买,AKESO股票实时行情,购买美股,购买港股,港股开户,美股开户,美股交易,港股交易,开通美港股账户,老虎国际行情","social":{"og_title":"AKESO(09926),Stock Price, Discussion, News, Quote & History - To The Moon - Tiger Brokers Online Investing Community","og_description":"Find the latest AKESO(09926) stock quote, history, news, and investing ideas from To The Moon - Tiger Brokers Online Investing Community to stay on top of the markets.","og_image":"https://community-static.tradeup.com/news/9b6dafd60190235ae8e2c95f52c583a0"}}}